Statement of Significance (as of designation - October 9, 1960):
Established in June 1770 by Father Junipero Serra, the Mission Church of San Carlos de Borromeo served as the headquarters for the "padre presidente" and was thus the most important of the California missions. By 1852 it lay in ruins. Since that time it has been restored and reconstructed, and today is an excellent example of a California mission.
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