Statement of Significance (as of designation - November 13, 1966):
Representative of the influence of German immigrants on beer brewing industry in America, this company, begun in 1852 by Eberhard Anheuser who in 1865 was joined by his son-in-law, Adolphus Busch, pioneered the use of new methods of production and distribution, including the invention of the refrigerated railroad car. These buildings, dating from the last quarter of the 19th century, are of brick, ornamented on the exterior with gargoyles and other figures.

Condition:
Anheuser-Busch continues to add new buildings and enlarge older ones. Many of the new structures are metal siding - covered steel frames, several stories tall, constructed around the huge tanks necessary to the production of beer at the "world's largest brewery." Alterations in the process of beer production and sharp increases in the volume of the that production have required enhancing the air There are no new threats to the NHL.

Anheuser Busch has pursued tax credit projects as the company has rehabilitated various older buildings. The company completed preliminary draft documentation that provides more detailed information about the buildings included in the historic district.